misconceptions about grapefruit juice interactions
February 2007
There are still misconceptions about grapefruit juice interactions.
We've known for years that grapefruit inhibits CYP3A4 and P-glycoprotein in the gut...and that this increases levels of some calcium channel blockers (felodipine, etc), statins (lovastatin, simvastatin), anti-arrhythmics (amiodarone), and others.
But misunderstandings still cloud the best way to handle this.
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